Effect of intraoperative optimization of regional cerebral oxygen saturation intervention on postoperative delirium in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass
10.3760/cma.j.cn131073-20240908-00404
- VernacularTitle:术中局部脑氧饱和度优化干预对CPB下心脏手术患儿术后谵妄的影响
- Author:
Shuhui HOU
1
;
Wei ZHONG
;
Lin QIU
;
Bo ZHAO
;
Taibing FAN
;
Junhui ZHOU
;
Yibao ZHANG
;
Hongqi LIN
;
Zhibin LANG
Author Information
1. 河南大学人民医院 阜外华中心血管病医院 河南省人民医院麻醉与围术期医学科，郑州 450000
- Publication Type:Journal Article
- Keywords:
Delirium;
Postoperative complications;
Regional cerebral oxygen saturation;
Children;
Cardiopulmonary bypass;
Cardiac surgical procedures
- From:
Chinese Journal of Anesthesiology
2025;45(4):410-414
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of intraoperative optimization of regional cerebral oxygen saturation(rSO 2C) intervention on postoperative delirium(POD) in pediatric patients undergoing cardiac surgery with cardiopulmonary bypass(CPB). Methods:Two hundred and seventy-three pediatric patients of both sexes, aged 28 days-6 yr, with American Society of Anesthesiologists Physical Status classification ≤Ⅳ, scheduled for elective cardiac surgery under CPB, were divided into intervention group( n=136) and control group( n=137) based on the computer random coding. In intervention group, optimized intervention measures were given when rSO 2C was below 75% of the baseline value for more than 1 min. In control group, rSO 2C was not monitored during operation, and intraoperative management was performed according to the routine monitoring indicators of pediatric cardiac surgery under CPB. The occurrence of POD within 7 days after operation was evaluated, and the duration and first occurrence time of POD were recorded. Results:Compared with control group, no significant change was found in the incidence of POD( P>0.05), the first occurrence time of POD was significantly prolonged, and the duration of POD was shortened in intervention group( P<0.05). Conclusions:Intraoperative optimization of rSO 2C intervention can delay the time to the first occurrence of POD and shorten the duration in pediatric patients undergoing cardiac surgery under CPB.
