Evaluation and Factor Analysis of Preoperative Medication-Related Issues in Patients Undergoing Video-Assisted Thoracoscopic Surgery
10.3870/j.issn.1004-0781.2025.05.015
- VernacularTitle:电视胸腔镜手术患者术前药物相关问题评价及影响因素分析
- Author:
Yingkun LIU
1
;
Ning PANG
;
Chaoqun MA
;
Rongrong FAN
;
Yi LIU
;
Yanguo LIU
;
Lin HUANG
;
Xiaohong ZHANG
Author Information
1. 北京大学人民医院药学部,北京 100044;赤峰学院附属医院药学部,赤峰 024000
- Publication Type:Journal Article
- Keywords:
Drug-related problems;
Video-assisted thoracoscopic surgery;
Pharmaceutical Care Network Europe Classi-fication System
- From:
Herald of Medicine
2025;44(5):764-770
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate drug-related problems(DRPs)and to analyze the influencing factors of patients un-dergoing video-assisted thoracoscopic surgery(VATS)before operation in thoracic surgery.Methods Clinical pharmacists used the Pharmaceutical Care Network Europe(PCNE)classification system(version 9.1)to analyze DRPs and influencing fac-tors of patients who received VATS from March 1 to May 31,2023,and had at least one comorbidity.Results Out of 300 pa-tients,174 were involved in a total of 200 DRPs.The most common category of DRPs is treatment safety(47.50％),followed by treatment effectiveness(46.00％)and others(6.50％).The most common cause of the problem is drug selection(33.83％),fol-lowed by other(33.33％)and patient cause(19.90％).367 interventions were conducted for DRPs,with the most interventions being at the drug level(55.86％),followed by the doctor level(39.24％)and the patient level(3.54％).In the end,96.00％of the intervention plan was accepted,and 86.50％of the problems were resolved.There were significant differences(P＜0.05)in the number of underlying diseases,medication varieties,body mass index(BMI),and length of hospital stay between the group with and without DRPs.The results of multivariate analysis showed that comorbidities,number of medication types,and BMI were independent risk factors for preoperative occurrence(or potential)of DRPs in VATS patients in thoracic surgery(OR＞1,P＜0.05).Conclusions Clinical pharmacists can effectively evaluate preoperative DRPs in patients undergoing VATS in thoracic surgery through the PCNE classification system.Comorbidities,number of medications,and BMI are influential factors for the oc-currence of preoperative DRPs.Future clinical practice should focus on these risk factors to optimize treatment strategies and re-duce the occurrence of DRPs.
