The relationship between sarcopenia and related indicators and quality of life in elderly patients with hypertension
10.3969/j.issn.1673-9701.2025.28.011
- VernacularTitle:老年高血压患者肌少症及相关指标与生存质量的关系
- Author:
Wenjing HU
1
;
Yuanyuan SUN
;
Xiujun CHENG
;
Jun XIE
Author Information
1. 安徽医科大学,安徽 合肥 230032;合肥市第二人民医院全科医学科,安徽 合肥 230011
- Publication Type:Journal Article
- Keywords:
Sarcopenia;
Quality of life;
Hypertension;
Blood pressure variability
- From:
China Modern Doctor
2025;63(28):48-52
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between sarcopenia and related indicators and quality of life in the elderly hypertensive population.Methods A total of 104 elderly patients with hypertension who were hospitalized in the Second People's Hospital of Hefei from January to December 2024 were selected as research subjects.The general information,biochemical indicators,blood pressure variability,skeletal muscle mass index,grip strength and walking speed of patients were collected,and the quality of life was evaluated by World Health Organization quality of life-brief version(WHOQOL-BREF).Patients were divided into non-sarcopenia group(n=46)and sarcopenia group(n=58)based on the presence or absence of sarcopenia.The clinical data and quality of life of patients in two groups were compared.Results There were statistically significant differences in gender,age,body mass index,serum albumin,24-hour systolic blood pressure coefficient of vatiation(SCV),24-hour diastolic blood pressure coefficient of vatiation(DCV)and WHOQOL-BREF score between two groups of patients(P＜0.05).Sarcopenia was negatively correlated with the quality of life in the physical and psychological domains(P＜0.05),but not correlated with the quality of life in the social relationship and environmental domains(P＞0.05).Both 24-hour SCV and 24-hour DCV were risk factors for quality of life in the physiological and psychological domains,while serum albumin was a protective factor for the quality of life in the physiological and psychological domains(P＜0.05).Conclusion Sarcopenia,serum albumin,24-hour SCV and 24-hour DCV in elderly hypertensive population are all correlated with the quality of life in the physiological and psychological domains.Attention should be paid to the physical function training of such people,ensuring adequate nutritional intake,actively detecting and reducing blood pressure variability to improve the overall quality of life.
