Research progress of immune metabolic regulation in inflammatory bowel disease
10.3760/cma.j.cn101480-20240829-00100
- VernacularTitle:炎症性肠病中的免疫代谢调控相关研究进展
- Author:
Tianzhuo ZHANG
1
;
Xiaolin YE
;
Dongdan LI
;
Xiaoshuang CUI
;
Jie WU
Author Information
1. 国家儿童医学中心 首都医科大学附属北京儿童医院消化科，北京 100045
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
Immune metabolism;
Glycolysis;
Fatty acid;
Amino acid
- From:
Chinese Journal of Inflammatory Bowel Diseases
2025;09(4):358-362
- CountryChina
- Language:Chinese
-
Abstract:
Immune dysregulation is a critical factor in the pathogenesis of inflammatory bowel disease (IBD), and numerous studies have focused on the impact of immune cell metabolic pathways. Immune system cells dynamically adapt to the microenvironment, regulating the body's response to external stimuli through intricate metabolic pathways. This review summarizes the mechanisms by which glycolysis, fatty acid and amino acid metabolisms influence immune metabolism and thereby modulate IBD progression, offering new perspectives for the diagnosis and treatment of IBD.
