Influencing factors for neurological function recovery in patients with type 2 diabetes mellitus complicated with acute cerebral infarction
10.3969/j.issn.1006-6187.2025.05.006
- VernacularTitle:2型糖尿病合并急性脑梗死患者神经功能恢复状态影响因素的研究
- Author:
Xiuting HUANG
1
;
Pei LI
1
Author Information
1. 100043 首都医科大学附属北京朝阳医院全科医学科
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus,type 2;
Acute cerebrovascular disease;
Modified Rankin scale;
Lipoprotein a
- From:
Chinese Journal of Diabetes
2025;33(5):345-349
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influencing factors for neurological function recovery in patients with acute cerebral infarction(ACI)and type 2 diabetes mellitus(T2DM).Methods A total of 156 patients with ACI(ACI group)and 266 patients with T2DM combined with ACI(T2DM+ACI group)hospitalized in our hospital were enrolled in this study from December 2016 to February 2020.The recovery degree in two weeks was evaluated according to the modified Rankin scale(m-RS)score in T2DM combined with ACI.The T2DM+ACI group was further divided into a good subgroup with a score of<1(n=50)and a poor subgroup with a score of≥1(n=216).Clinical characteristics were compared between the two groups.Pearson correlation analysis was used to analyze the correlation between m-RS score and other indicators.Multiple linear regression analysis was used to analyze the influencing factors for m-RS score.Results The levels of FPG,HbA1c and TG were higher in T2DM+ACI group than in ACI group(P<0.05).The poor subgroup had significantly higher age and LP(a)than the good subgroup(P<0.05),and significantly lower LDL-C,TG,and serum uric acid than the good subgroup(P<0.05).Pearson correlation analysis showed that m-RS score was positively correlated with age,sex and LP(a)(r=0.227,0.170,0.157;P=0.000,0.005,0.011).Multiple linear regression analysis showed that age and LP(a)were the influencing factors for m-RS score.Conclusions LP(a)a is a influencing factor for neurological function recovery in patients with T2DM combined with ACI,and clinical attention should be paid to the level of LP(a)a in such patients.
