Analysis of the Chemical Compositions of Olibanum of Different Origins Based on UPLC-Q/TOF-MS Combined with Multi-variate Statistics Methods
10.14148/j.issn.1672-0482.2025.0668
- VernacularTitle:基于UPLC-Q/TOF-MS结合多元统计学方法分析不同来源乳香的化学成分
- Author:
Qin HE
1
;
Ganming YAN
;
Haixia YIN
;
Na ZHU
;
Yi WU
;
Guocai LI
Author Information
1. 扬州大学医学院,江苏 扬州 225009;苏州市中西医结合医院药剂科,江苏 苏州 215000
- Publication Type:Journal Article
- Keywords:
Olibanum;
chemical compositions;
different origins;
multivariate statistics methods;
triterpenes
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2025;41(5):668-677
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To analyze the differential chemical composition of Olibanum of different origins and to provide some references for the identification of Olibanum origin and the quality standards.METHODS The chemical compositions of Olibanum were analyzed by UPLC-Q/TOF-MS.Multivariate statistical methods were used to analyze Olibanum and processed products to screen the differential compounds in Olibanum of different origins.RESULTS Using positive and negative ion scanning modes,a total of 108 compounds were identified in Olibanum.The compounds were mainly terpenes,among which triterpenes were the highest.And through multivariate statistical analysis,it was found that there were significant differences in the chemical compositions of Olibanum of different regions,with a total of 34 differential compounds;furthermore,specific compounds unique to Olibanum from other sources were identified.CONCLUSION Different regions of Olibanum could be distinguished based on their differential chemical composi-tions.This study could serve as a basis for identifying different origins of Olibanum,and also provide experimental data for subsequent research on the pharmacological substance basis of Olibanum.
