Research progress on the comorbidity mechanism of inflammatory bowel disease and IgA nephropathy
10.3760/cma.j.cn101480-20241014-00112
- VernacularTitle:炎症性肠病与IgA肾病共病机制的研究进展
- Author:
Yanhang LI
1
;
Qin WANG
;
Zhijun CAO
Author Information
1. 上海交通大学医学院附属仁济医院消化科 200127
- Publication Type:Journal Article
- Keywords:
Inflammatory bowel disease;
IgA nephropathy;
Extra-intestinal manifestations
- From:
Chinese Journal of Inflammatory Bowel Diseases
2025;09(4):334-338
- CountryChina
- Language:Chinese
-
Abstract:
After Hubert first reported cases of IgA nephropathy (IgAN) associated with inflammatory bowel disease (IBD) in 1984, researches further confirmed the association. Genome-wide association analyses also suggested that they may share a common genetic background. As IgAN is one of the leading causes of kidney failure and chronic kidney disease (CKD), early diagnosis and intervention can significantly improve the prognosis, and strengthening renal function follow-up and IgAN screening in IBD patients helps disease management. This article reviews the interplay between IBD and IgAN to provide reference for clinical diagnosis and treatment.
