The application progress of nanomaterials in atherosclerotic cardiovascular disease
- VernacularTitle:纳米材料在动脉粥样硬化性心血管疾病中的应用进展
- Author:
Zihao DENG
1
;
Xinyang HUANG
;
Kunjiang ZHONG
;
Bo ZHAO
Author Information
- Publication Type:Journal Article
- Keywords: atherosclerosis; nanotechnology; drug carriers; drug delivery systems; cardiovascular diseases
- From: Tianjin Medical Journal 2025;53(5):556-560
- CountryChina
- Language:Chinese
- Abstract: Atherosclerotic cardiovascular diseases(ASCVD)are chronic progressive diseases characterized by endothelial dysfunction,and their traditional therapies have limitations.In recent years,nanocarrier systems have demonstrated significant advantages in targeted delivery,enhancing drug safety and efficacy,thereby offering new strategies for precise diagnosis and treatment of ASCVD.Nanomaterials,including polymer nanoparticles,lipid nanoparticles,inorganic nanoparticles and bio-inspired nanoparticles,can effectively intervene key pathological processes of ASCVD.They achieve therapeutic effects by regulating macrophage balance,preserving endothelial cell function,maintaining smooth muscle cell contractile phenotype and modulating platelet activity.This review summarizes the application characteristics and research progress of different types of nanomaterials in the prevention and treatment of ASCVD,and provides insights into the challenges and future prospects of this field.
