Application of three-dimensional CT values in differential diagnosis of active and inactive pulmonary tuberculosis
10.3969/j.issn.1005-202X.2025.10.010
- VernacularTitle:三维CT值在活动性与非活动性肺结核鉴别诊断中的应用
- Author:
Zhifei ZHANG
1
;
Rui CHEN
1
;
Zonghua CAO
1
;
Quanwu ZHANG
1
;
Zhiyong WANG
1
;
Xiaohui CHEN
1
Author Information
1. 陕西省结核病防治院(陕西省第五人民医院)影像中心,陕西 西安 710100
- Publication Type:Journal Article
- Keywords:
active pulmonary tuberculosis;
inactive pulmonary tuberculosis;
three-dimensional CT value;
CT sign;
tuberculosis lesion;
differential diagnosis
- From:
Chinese Journal of Medical Physics
2025;42(10):1337-1341
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the differential diagnostic value of three-dimensional CT values in active pulmonary tuberculosis(APTB)and inactive pulmonary tuberculosis(IPTB).Methods A retrospective analysis was conducted on 96 patients with pulmonary tuberculosis.According to whether the pulmonary tuberculosis lesions were active,the patients were divided into APTB group(n=61)and IPTB group(n=35).The baseline data,CT signs,and three-dimensional CT values were compared between two groups.Additionally,the results of three-dimensional CT values and conventional CT reading method in evaluating the activity of pulmonary tuberculosis were compared,and the accuracy,sensitivity and specificity of using three-dimensional CT values and conventional CT reading method to evaluate the activity of pulmonary tuberculosis were further analyzed.Results APTB group showed a higher incidence of bilateral pulmonary lesions than IPTB group(P<0.05).Compared with IPTB group,APTB group had higher proportions of blurred boundaries,parenchymal cavities,ground-glass opacities,and tree-in-bud signs(P<0.05),but lower proportions of parenchymal bronchiectasis,parenchymal calcifications,and fibrous strip shadows(P<0.05).The three-dimensional CT values in APTB group were lower than those in IPTB group(P<0.05).Significant differences were observed between conventional CT reading method and three-dimensional CT values in evaluating the activities of pulmonary parenchymal calcifications and thick-wall cavities(P<0.05).Specifically,three-dimensional CT values correctly identified 92 cases of tuberculosis lesions,including 59 cases of APTB and 33 cases of IPTB,and the remaining 4 misidentified lesions were calcified,consolidated and nodular lesions.Conventional CT reading method correctly identified 68 cases of tuberculosis lesions,including 43 cases of APTB and 25 cases of IPTB.The sensitivity,specificity,and accuracy of three-dimensional CT values were all higher than those of conventional CT reading method(P<0.05).Conclusion Three-dimensional CT values can effectively determine the activity of pulmonary tuberculosis,exhibiting high sensitivity,specificity,and accuracy.
