Comparative study on the safety and efficacy of oral sulfate solution and polyethylene glycol in intestinal preparation before colonoscopy
- VernacularTitle:硫酸镁钠钾与聚乙二醇电解质散在肠镜检查前肠道准备中的安全性和有效性的对比研究
- Author:
Qiuke HOU
1
;
Jiaman LIN
;
Jiahe ZHANG
;
Xiling YANG
;
Chunhong HU
;
Qi LUO
Author Information
- Publication Type:Journal Article
- Keywords: oral sulfate solution(OSS); polyethylene glycol(PEG); colonoscopy; intestinal preparation; intestinal cleanliness
- From: China Journal of Endoscopy 2025;31(10):48-54
- CountryChina
- Language:Chinese
- Abstract: Objective To compare the safety and efficacy of oral sulfate solution(OSS)and compound polyethylene glycol(PEG)for intestinal preparation before colonoscopy.Methods A retrospective analysis was conducted on 2,000 patients who underwent intestinal preparation before colonoscopy using OSS and PEG from September 2023 to September 2024.According to different intestinal preparation drugs,the patients were divided into the OSS group(1 000 cases,oral OSS)and the PEG group(1 000 cases,oral 4 L PEG).The intestinal cleanliness,cleaning effect,intestinal cavity bubbles,positive rate of colonoscopy and incidence of adverse reactions were compared between the two groups of patients.Results The evaluation results of cleaning effect showed that the success rate of intestinal preparation was 92.5%(925/1 000)in the OSS group and 91.7%(917/1 000)in the PEG group,with no statistical significance between the two groups(P>0.05).The results of Boston bowel preparation scale(BBPS)score showed that there was no statistical significance between the two groups in left colon score(P>0.05),but the total score,middle and right colon score in OSS group were higher than those in PEG group,with statistical significance(P<0.05).The results of intestinal bubble evaluation showed that the satisfaction rate of bubble evaluation in OSS group(96.2%)was higher than that in PEG group(90.3%),the difference was statistically significant(P<0.05).There was no significant difference in the positive rate of colonoscopy and the incidence of adverse events between the two groups(P>0.05).Conclusion OSS has a good defoaming effect in intestinal preparation,and its cleaning effect is comparable to that of PEG,with high safety.
