Application of metabolomics in anxiety disorders
10.12007/j.issn.0258-4646.2025.05.014
- VernacularTitle:代谢组学在焦虑障碍中的应用
- Author:
Xiyue ZHANG
1
;
Xiaojun SHAO
;
Yongzhong LIN
;
Gang ZHU
Author Information
1. 中国医科大学附属第一医院精神科,沈阳 110001;大连医科大学附属第二医院神经内科,辽宁 大连 116027
- Publication Type:Journal Article
- Keywords:
anxiety disorder;
metabolomics;
biomarker
- From:
Journal of China Medical University
2025;54(5):461-465
- CountryChina
- Language:Chinese
-
Abstract:
Anxiety disorders are psychiatric conditions characterized by high prevalence,chronicity,and comorbidity.The World Health Organization has listed anxiety disorders as a cause of health-related disabilities.Metabolomics can be used to qualitatively and quantita-tively analyze metabolites in organisms using modern analytical techniques,comprehensively revealing the overall characteristics of meta-bolic changes in the body and providing novel insights into diseases.It is important to identify potential biomarkers associated with anxiety disorders by investigating perturbations in metabolites and metabolic pathways in patients with anxiety disorders.This review addresses the application of metabolomics in anxiety disorders to provide a basis for revealing their pathogenesis,early diagnosis,and efficacy evalu-ation.