Diagnosis and treatment of Crohn′s disease-related anorectal stricture
10.3760/cma.j.cn101480-20230331-00045
- VernacularTitle:克罗恩病肛管直肠狭窄的诊断与治疗
- Author:
Qi CHEN
1
;
Lichao QIAO
1
;
Yuxia GONG
1
;
Ping ZHU
1
;
Bolin YANG
1
Author Information
1. 南京中医药大学附属医院肛肠科,南京 210029
- Publication Type:Journal Article
- Keywords:
Crohn′s disease;
Anorectal stricture;
Diagnosis;
Treatment
- From:
Chinese Journal of Inflammatory Bowel Diseases
2023;07(3):220-226
- CountryChina
- Language:Chinese
-
Abstract:
Crohn′s disease (CD) -related anorectal stricture is a narrowing lesion that occurs in the distal part of the gastrointestinal tract. The symptoms of anorectal stricture in CD are not obvious in the early stage, but in the later stage, manifest difficulty in defecation, fecal incontinence, and persistent anal pain, often requiring repeated medical and surgical treatment, leading to a dramatic decrease in the patient′s quality of life. The presence of anorectal stricture in patients with CD usually indicates that the intestinal tract, especially rectal inflammation, is not controlled, and the probability of diverting stoma or rectal resection is significantly increased. Clinical diagnosis requires comprehensive detailed physical examination, endoscopy and biopsy, magnetic resonance imaging, etc. Treatment is based on medical therapy, supplemented by endoscopic and instrumental anal surgical intervention when necessary, but there is a lack of standardized treatment protocols. This article reviews the existing pathogenesis, diagnosis, and treatment modalities of this disease to help with clinical diagnosis and treatment.