Influencing factors of non-reversal mild cognitive impairment patients after stroke
10.3760/cma.j.cn115682-20250102-00014
- VernacularTitle:首发脑卒中后轻度认知障碍患者未逆转的影响因素分析
- Author:
Yan ZHANG
1
;
Beibei NIE
1
;
Xue LI
1
;
Dandan GUO
1
;
Hailing SONG
1
Author Information
1. 郑州大学第一附属医院神经内科,郑州 450000
- Publication Type:Journal Article
- Keywords:
Stroke;
Mild cognitive impairment;
Non-reversal;
Influencing factor
- From:
Chinese Journal of Modern Nursing
2025;31(28):3874-3878
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the factors influencing the non-reversal of mild cognitive impairment (MCI) after a first stroke.Methods:A total of 243 first stroke patients with MCI were enrolled at the First Affiliated Hospital of Zhengzhou University from March 2020 to March 2023. The patients were followed up for one year to assess the reversal of MCI. Patients who did not undergo reversal and those who did undergo reversal were included in non-reversal group and reversal group, respectively. General information of non-reversal group and reversal group was compared. Binary Logistic regression was used to analyze the factors influencing the non-reversal of MCI after a first stroke.Results:After one year of follow-up, the non-reversal rate was 25.10% (61/243) among 243 first stroke patients with MCI. Binary Logistic regression analysis showed that older age, history of diabetes, high National Institute of Health Stroke Scale (NIHSS) score at admission, left-sided lesions, and modified Fazekas grade 3 were risk factors for non-reversal of MCI after a first stroke ( P<0.05), while educational level of college degree or above was a protective factor ( P<0.05) . Conclusions:Older age, history of diabetes, high NIHSS score at admission, left-sided lesions, and modified Fazekas grade 3 are risk factors for non-reversal of MCI after a first stroke, while an educational level of college degree or above is a protective factor.