Effects of microscopic total resection on cerebral blood flow perfusion and cognitive function in patients with glioma
- VernacularTitle:显微镜下全切术对脑胶质瘤患者脑血流灌注及认知功能的影响
- Author:
Zi-yu ZHU
1
;
Xiao-dong LIU
1
;
Bao QIAN
1
Author Information
- Publication Type:Journal Article
- Keywords: glioma; microscopic total resection; cerebral blood flow perfusion; cognitive function; recurrence
- From: Journal of Regional Anatomy and Operative Surgery 2025;34(10):900-903
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the effects of microscopic total resection on cerebral blood flow perfusion and cognitive function in patients with glioma.Methods The clinical data of 80 glioma patients admitted to our hospital were retrospectively analyzed.The grouping were conducted according to different surgical methods,among which 38 patients treated with traditional craniotomy were included in the traditional group,and 42 patients treated with microscopic total resection were included in the microscopic group.The surgery-related indicators,cerebral blood perfusion indexes,cognitive function and recurrence of patients in the two groups were compared.Results The surgical time,time to get out of bed,and hospital stay of patients in the microscopic group were shorter than those in the traditional group,the intraoperative blood loss was lower than that in the traditional group,and the incision length was smaller than that in the traditional group,with statistically significant differences(P<0.05).Six months after surgery,the standard uptake value of 13N-NH3 in the cerebral cortex of patients in the microscopic group was higher than that in the traditional group(P<0.05).Six months after surgery,the scores of directional ability,immediate memory,attention and calculation ability,delayed memory,and language function,and total mini-mental state examination score of patients in the microscopic group were higher than those in the traditional group(P<0.05).One year after surgery,the recurrence rate of patients in the microscopic group was 4.76%,which was lower than that in the traditional group of 23.68%,with statistically signifi-cant difference(P<0.05).Conclusion Compared with traditional craniotomy,microscopic total resection is more advantageous for patients with glioma,which can optimize surgical indicators,ameliorate postoperative cerebral blood flow perfusion,and restore cognitive function,with a lower postoperative recurrence rate.
