Risk factors for depression in patients with type 2 diabetes mellitus: a Meta-analysis
10.3760/cma.j.cn115682-20241030-05913
- VernacularTitle:2型糖尿病患者并发抑郁危险因素的Meta分析
- Author:
Xin GE
1
;
Rong XU
;
Shuya ZHANG
Author Information
1. 武汉大学人民医院内分泌科，武汉 430060
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus, type 2;
Depression;
Risk factors;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2025;31(21):2862-2868
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically analyze risk factors for depression in patients with type 2 diabetes mellitus (T2DM) .Methods:PubMed, Embase, Web of Science, Cochrane Library, China National Knowledge Infrastructure, Wanfang Data, and VIP were searched for literature on risk factors for T2DM combined with depression from the establishment of the database to April 30, 2023. Literature was screened and data was extracted independently by two researchers and meta-analysis was performed using RevMan 5.3.Results:A total of 38 papers were included. Meta-analysis of 10 risk factors showed that comorbidity with other chronic somatic diseases [ OR=2.89, 95% CI (1.70, 4.91) ] , diabetic retinopathy [ OR=2.64, 95% CI (1.74, 4.01) ] , number of comorbidities [ OR=2.15, 95% CI (1.84, 2.51) ] , occurrence of comorbidities [ OR=2.00, 95% CI (1.67, 2.40) ] , insulin therapy [ OR=1.91, 95% CI (1.42, 2.57) ] , duration of the disease [ OR=2.04, 95% CI (1.61, 2.59) ] , triglycerides [ OR=1.40, 95% CI (1.11, 1.77) ] , and glycosylated hemoglobin [ OR=1.52, 95% CI (1.28, 1.80) ] were risk factors for T2DM combined with depression. Conclusions:Depression in patients with type 2 diabetes is the result of multiple risk factors acting together. Clinicians should strengthen the identification of risk factors and take early intervention measures.
