Latent profile analysis and influencing factors of cancer-related fatigue in breast cancer patients during the rehabilitation phase
10.3760/cma.j.cn115682-20241031-05926
- VernacularTitle:康复期乳腺癌患者癌因性疲乏的潜在剖面分析及其影响因素研究
- Author:
Tianchao CHEN
1
;
Yuanmei LAN
;
Yueying FENG
;
Haoqi WU
;
Xinjuan WU
Author Information
1. 中国医学科学院北京协和医院护理部，北京 100730
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Cancer-related fatigue;
Rehabilitation phase;
Latent profile analysis
- From:
Chinese Journal of Modern Nursing
2025;31(21):2869-2876
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the latent profile characteristics of cancer-related fatigue (CRF) in breast cancer patients during the rehabilitation phase and to analyze the influencing factors of different latent profiles.Methods:A convenience sampling method was used to recruit 190 breast cancer patients in the rehabilitation phase from the follow-up cohort at Peking Union Medical College Hospital between March and May 2024. Data was collected using a general information questionnaire, the Cancer Fatigue Scale, the Self-Rating Anxiety Scale, the Self-Rating Depression Scale, the Pittsburgh Sleep Quality Index and the Visual Analogue Scale. Logistic regression analysis was conducted to identify the influencing factors of CRF latent profiles. A total of 190 questionnaires were distributed, and 183 valid responses were collected, yielding an effective response rate of 96.32% (183/190) .Results:Three latent profiles of CRF were identified: mild fatigue, moderate fatigue, and severe fatigue. Menopausal status, depressive symptoms, and pain scores were significant influencing factors of the CRF latent profiles ( P<0.05) . Conclusions:Cancer-related fatigue in breast cancer patients during the rehabilitation phase exhibits distinct latent profile characteristics. Early identification of profile types and associated influencing factors may provide a scientific basis for healthcare professionals to develop targeted clinical interventions to help patients alleviate fatigue.
