Investigation on symptom clusters and sentinel symptom of patients with urinary sepsis
10.3760/cma.j.cn115682-20240812-04499
- VernacularTitle:尿源性脓毒症患者症状群及前哨症状的调查研究
- Author:
Wei XIE
1
;
Zhengguo ZHANG
1
;
Weiyue ZHANG
1
Author Information
1. 郑州大学第一附属医院泌尿外科，郑州 450052
- Publication Type:Journal Article
- Keywords:
Urinary sepsis;
Symptom cluster;
Sentinel symptom;
Flank pain;
Abdominal pain;
Urinary urgency
- From:
Chinese Journal of Modern Nursing
2025;31(19):2631-2635
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore symptom clusters and sentinel symptoms in patients with urinary sepsis.Methods:A retrospective study was conducted using convenience sampling. A total of 127 patients who developed urinary sepsis after endoscopic lithotripsy in the Department of Urology at the First Affiliated Hospital of Zhengzhou University from January 2020 to December 2023 were included. Basic patient information and symptom data were collected through the hospital's electronic medical record system. Symptom clusters were identified using exploratory factor analysis, and sentinel symptoms were determined based on the Apriori algorithm.Results:The top 10 most frequent symptoms among the 127 patients with urinary sepsis were: flank pain, urinary urgency, burning sensation during urination, fever, increased urinary frequency, abdominal pain, painful urination, myalgia, chills, and nausea. The most common symptom was flank pain (84.25%, 107/127), followed by urinary urgency (70.87%), burning urination (63.72%), and fever (62.99%). Three symptom clusters were identified: somatic cluster (flank pain-fever-myalgia-chills-drowsiness), gastrointestinal cluster (abdominal pain-nausea-vomiting), and urinary tract cluster (urgency-burning-frequency-painful urination), explaining 51.33% of the total variance. Apriori analysis indicated that flank pain, abdominal pain, and urinary urgency were sentinel symptoms for the somatic, gastrointestinal, and urinary clusters, respectively.Conclusions:Patients with urinary sepsis often experience a combination of somatic, gastrointestinal, and urinary symptom clusters. Among them, gastrointestinal symptoms are atypical. Flank pain, abdominal pain, and urinary urgency may serve as sentinel symptoms for their respective clusters and warrant early clinical attention.
