Study on density variations of hydroxyapatite(water)within lumbar vertebral bodies based on spectral CT material decomposition technique
10.3969/j.issn.1002-1671.2025.07.023
- VernacularTitle:基于能谱CT物质分离技术对腰椎椎体内羟基磷灰石(水)密度差异的研究
- Author:
Xiaoqin QU
1
;
Nuo CHEN
;
Jie DENG
;
Quanjun ZHENG
;
Kuan LU
;
Lihua QIU
Author Information
1. 宜宾市第二人民医院医学影像中心,四川 宜宾 644000;西南医科大学附属医院放射科,四川 泸州 646000
- Publication Type:Journal Article
- Keywords:
gemstone spectral imaging;
computed tomo-graphy;
material decomposition technique;
bone mineral density;
osteoporosis
- From:
Journal of Practical Radiology
2025;41(7):1186-1189
- CountryChina
- Language:Chinese
-
Abstract:
Objective To quantitatively measure the density of hydroxyapatite(HAP)(water)within lumbar vertebral bodies using the gemstone spectral imaging(GSI)material decomposition technique and to compare and analyze the clinical significance of density variations of HAP(water)in different regions of L1-L3 vertebral bodies.Methods A total of 242 patients who underwent lumbar quantitative computed tomography(QCT)scans via utilizing the GSI technique were selected.Following the scans,the HAP(water)density values in four regions(anterosuperior,posterosuperior,anteroinferior,and posteroinferior)of each L1-L3 vertebral bodies were quantitatively measured using the material decomposition technique.Based on the QCT results,all cases were divided into three groups of normal bone mineral density,osteopenia,and osteoporosis.The distributions of HAP(water)density values in the four regions within each vertebral body were compared and analyzed among the groups.Results In all three groups of patients,the highest HAP(water)density values in the L1-L3 vertebral bodies were all located in the posteroinferior region,followed by the posterosuperior region.In the normal bone mineral density group,the lowest HAP(water)density values was found in the anterosuperior region of the L1 vertebral body.In the osteopenia and osteoporosis groups,the lowest HAP(water)density values was found in the anteroinferior region of the L1-L3 vertebral bodies.Conclusion Significant differences in HAP(water)density are present across different regions within lumbar vertebral bodies,which may be related to the development of vertebral osteoporosis and the location of fractures.
