Risk factors for postoperative complications in patients undergoing implant-based breast reconstruction after mastectomy
10.7659/j.issn.1005-6947.250078
- VernacularTitle:乳腺切除后植入物乳房重建患者术后并发症的危险因素分析
- Author:
Yanni HUANG
1
;
Dongbo ZHANG
1
;
Jiang LIU
1
;
Haiyu LIU
1
;
Wei WU
1
Author Information
1. 中山大学孙逸仙纪念医院逸仙乳腺肿瘤医院 乳腺外科,广东 广州 510120
- Publication Type:Journal Article
- Keywords:
Mastectomy,Radical;
Mammaplasty;
Breast Implants;
Postoperative Complications;
Risk Factor
- From:
Chinese Journal of General Surgery
2025;34(5):945-952
- CountryChina
- Language:Chinese
-
Abstract:
Background and Aims:Implant-based breast reconstruction is one of the most common reconstructive approaches after mastectomy for breast cancer.However,the incidence of postoperative complications remains significant,and the associated risk factors have not been fully elucidated.This study aimed to analyze the incidence of surgical complications following implant-based breast reconstruction in patients undergoing mastectomy at our center and to identify potential risk factors.Methods:A retrospective analysis was conducted on patients who underwent mastectomy and implant-based breast reconstruction at Sun Yat-sen Memorial Hospital between May 2004 and August 2022.Patients were grouped according to the presence or absence of postoperative surgical complications,and multivariate Logistic regression was used to identify independent risk factors.Results:A total of 545 patients with 602 reconstructed breasts were included.Surgical complications occurred in 13.6%(82/602)of the cases,including infection,wound dehiscence/poor healing,flap or nipple-areola necrosis,and implant leakage/rupture.Multivariate analysis revealed that nipple-areola complex resection(OR=1.934,95%CI=1.056-3.542,P=0.033),postoperative radiotherapy(OR=2.483,95%CI=1.527-4.036,P<0.001),implant volume≥300 mL(OR=1.663,95%CI=1.025-2.696,P=0.039),and surgeon experience with fewer than 10 cases(OR=1.804,95%CI=1.092-2.979,P=0.021)were all independent risk factors for complications.Conclusion:NAC resection,radiotherapy,large implant volume,and limited surgical experience are important independent risk factors for postoperative surgical complications following implant-based breast reconstruction.Thorough preoperative evaluation and appropriate surgical planning are essential to minimize risks.
