A case report of female primary enteric adenocarcinoma of the urethra:3 surgeries and 39-month follow-up
10.3969/j.issn.1009-8291.2025.09.010
- VernacularTitle:1例女性原发性尿道肠型腺癌病例报告:3次手术和39个月随访
- Author:
Peili MA
1
;
Haitao DAI
;
Zhong ZHANG
;
Guanghai JI
;
Meiyuan ZHOU
;
Changwei PENG
Author Information
1. 长江大学附属第一医院泌尿外科,湖北荆州 434000
- Publication Type:Journal Article
- Keywords:
female;
primary urethral carcinoma;
enteric adenocarcinoma of the urethra
- From:
Journal of Modern Urology
2025;30(9):784-787
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristics and treatment methods of female primary enteric adenocarcinoma of the urethra.Methods The diagnosis and treatment of one case were reported.The origin,etiology,imaging findings,diagnosis,treatment,and prognosis were discussed in combination with relevant literature.Results The patient is a 61-year-old female,visited our hospital due to vaginal odor complicated with urethral bleeding for 2 months,and was diagnosed with urethral adenocarcinoma after examination.She underwent partial urethral resection,urethral meatus shaping and temporary bladder fistula surgery,with negative resection margins.However,local recurrence occurred 7 months after surgery.The patient was readmitted for a second time,undergoing laparoscopic total urethral resection,anterior vaginal wall resection,bladder neck resection,and permanent bladder fistulation,followed by chemotherapy.At the 19th month after the first surgery,the patient was admitted due to tumor recurrence,and the third surgery consisted of total bladder and uterus resection,ileal neobladder,and perineal closure.Postoperative pathology indicated urethral adenocarcinoma originating from the intestines.During the 39-month follow-up,the tumor recurred twice.No recurrence or metastasis was observed after the final total pelvic exenteration.Conclusion Enteric adenocarcinoma of the urethra is extremely rare.Comprehensive treatment including surgery,radiotherapy,and chemotherapy may prolong survival,but the overall prognosis is poor,requiring long-term follow-up.
