Preliminary preparation and framework construction for developing clinical prediction models
10.3760/cma.j.cn112338-20250114-00038
- VernacularTitle:临床预测模型开发的前期准备与框架构建
- Author:
Zichen YE
1
;
Jiahui WANG
;
Qu LU
;
Peng XUE
;
Yu JIANG
Author Information
1. 中国医学科学院北京协和医学院群医学及公共卫生学院，北京 100730
- Publication Type:Journal Article
- Keywords:
Clinical prediction model;
Model development;
Framework construction;
Data processing
- From:
Chinese Journal of Epidemiology
2025;46(8):1438-1445
- CountryChina
- Language:Chinese
-
Abstract:
Clinical prediction models, which utilize clinical data and statistical methods, aim to enhance the accuracy and efficiency of medical decision-making and improve patient health outcomes. These models play a crucial role in optimizing healthcare decisions and tailoring treatments to individual needs. However, many studies currently face systemic challenges during the development process, including unclear model design objectives, redundant model construction, lack of clinical relevance in variable selection, and irregular data preprocessing. These issues finally lead to reduced model performance and limited clinical applicability. To address these challenges, this study systematically reviews relevant literature, including articles from the BMJ, and draws on practical research experience to propose a structured preparation process. This process aims to provide a scientific guiding framework for model development, ensuring the efficiency of subsequent model construction and the accuracy of predictions, thus laying a foundation for the application and advancement of clinical prediction models.
