Heterogeneity in trajectories of perinatal depressive symptoms and associated factors
10.3969/j.issn.1000-6729.2025.08.09
- VernacularTitle:围产期抑郁发展轨迹的异质性及其相关因素
- Author:
Chen WANG
1
;
Anning LI
;
Jinqin HOU
;
Haili JIANG
Author Information
1. 首都医科大学附属北京妇产医院/北京妇幼保健院围产医学部,北京 100026
- Publication Type:Journal Article
- Keywords:
perinatal depression;
trajectory;
latent class growth model(LCGM);
risk factors
- From:
Chinese Mental Health Journal
2025;39(8):720-726
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the heterogeneity in the trajectories ofperinatal depressive symptoms and identify the related factors.Methods:A longitudinal follow-up study was conducted from January 2020 to June 2021.Baseline information,marriage satisfaction and social support status were collected at enrolment.Perinatal de-pressive symptoms were measured using the Edinburgh Postnatal Depression Scale(EPDS)at five time-points from second trimester to three-months postpartum.A Latent Class Growth Model(LCGM)was used to identify sub-groups of perinatal depressive symptoms trajectories and logistic regression was applied to examine associated risk and protective factors.Results:Two latent depression trajectory subgroups were identified A majority(72.2％,n=1 023)followed a curvilinear trajectory with low baseline scores that increased over time(curvilinear group),while 27.8％(n=393)maintained high,stable scores(linear group).Older age,higher marital satisfaction,and stronger social support were associated with a lower likelihood of belonging to the linear group(OR=0.96,0.94,0.89,re-spectively),while a personal or family history of depression increased this likelihood(OR=2.50,6.51).Conclusion:Trajectories of perinatal depressive symptoms vary significantly among individuals.The risk of persis-tent high-level symptoms is lowered by older age,stronger marital satisfaction,and greater social support,and heightened by a personal or family history of depression.
