Association between handgrip strength and chronic kidney disease in adult residents in Anhui Province
- VernacularTitle:安徽省成年居民握力与慢性肾脏病关联研究
- Author:
Wei XU
1
;
Guodie XIE
1
;
Jingyao HU
1
;
Dan DAI
1
;
Xiuya XING
1
;
Huadong WANG
1
;
Qin HE
1
;
Jingqiao XU
1
;
Yili LYU
1
;
Qianyao CHENG
1
;
Qinglian MENG
1
Author Information
- Publication Type:Journal Article
- Keywords: Handgrip strength; Chronic kidney disease; Adult resident; Cross-sectional study
- From: Chinese Journal of Epidemiology 2025;46(7):1231-1236
- CountryChina
- Language:Chinese
- Abstract: Objective:To explore the independent association between handgrip strength and chronic kidney disease (CKD) in adult residents in Anhui Province using data from the China Adult Chronic Disease and Risk Factor Surveillance (2023).Methods:A multi-stage stratified cluster random sampling method was used to select residents aged ≥18 years for surveys, physical measurements, and laboratory tests. Relevant covariates were adjusted, and a multivariable logistic regression model was established to infer the association between handgrip strength and CKD, followed by subgroup analysis.Results:A total of 7 295 participants were included in the study, with age of (61.5±13.2) years, and 55.6% of the study participants were women. The results of the multivariate logistic regression analysis showed that with each 1.0 kg increase in handgrip strength, the risk for CKD decreased by 1.3% ( OR=0.987, 95% CI: 0.978-0.997). Compared with those with low handgrip strength, the people with moderate hasdgrip strength ( OR=0.818, 95% CI: 0.694-0.964) and high handgrip strength ( OR=0.729, 95% CI: 0.598-0.989) had lower risk for CKD. In the subgroup analysis, the association between handgrip strength and risk for CKD remained unchanged regardless age, sex, smoking status, and alcohol consumption statuys, and the prevalence of hypertension and hyperlipidemia (interaction P>0.05), except BMI and diabetes. Conclusion:The decline in handgrip strength is associated with an increased risk for CKD in adult residents in Anhui.
