Progress in metabolomics of multiple myeloma
10.3760/cma.j.cn121090-20241205-00536
- VernacularTitle:多发性骨髓瘤代谢组学研究进展
- Author:
Xuan YE
1
;
Zhengxu SUN
1
;
Xiaoyan QU
1
;
Lei FAN
1
Author Information
1. 江苏省人民医院（南京医科大学第一附属医院）血液科，南京 210029
- Publication Type:Journal Article
- From:
Chinese Journal of Hematology
2025;46(10):980-984
- CountryChina
- Language:Chinese
-
Abstract:
Multiple myeloma (MM) is a malignant disease characterized by clonal plasma cell proliferation, with metabolic reprogramming. Abnormal metabolism of amino acids, glucose, lipids and nucleotides plays a crucial role in various pathological processes in MM, such as proliferation, metastasis, immune escaping and drug resistance. This review summarized the application of metabolomics technology in identifying biomarkers for MM and targeting related metabolic pathways. The objective is to guide further investigations into the metabolic mechanisms underlying MM and encourage innovation in clinical diagnosis and treatment strategies for this disease.
