Effectiveness of bleeding risk graded management program in patients undergoing catheter-directed thrombolysis
10.3760/cma.j.cn115682-20240626-03572
- VernacularTitle:出血风险分级管理方案在导管接触性溶栓患者中的应用
- Author:
Yan LI
1
;
Jingping GE
1
;
Yuanyuan YIN
1
;
Juan HE
1
;
Ping LIU
1
Author Information
1. 南京医科大学附属南京医院（南京市第一医院）介入血管科，南京 210006
- Publication Type:Journal Article
- Keywords:
Deep vein thrombosis;
Catheter-directed thrombolysis;
Risk of bleeding;
Graded management
- From:
Chinese Journal of Modern Nursing
2025;31(8):1011-1017
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the efficacy of a bleeding risk graded management program in patients with lower extremity deep vein thrombosis (DVT) undergoing catheter-directed thrombosis (CDT) .Methods:Convenience sampling was used to select 100 DVT patients who underwent CDT from October 2021 to December 2023 in the Nanjing First Hospital as study subjects. According to the propensity matching score ratio of 1: 1, patients were divided into control group and observation group, with 50 cases in each group. Control group implemented CDT routine nursing and rehabilitation exercises, and observation group implemented a bleeding risk graded management program based on control group by dynamically monitoring changes in plasma fibrinogen and blood pressure. Differences in the rates of swelling reduction in the limbs, venous patency, bleeding events and hospitalization satisfaction were compared between the two groups.Results:After the intervention, the swelling reduction rate of the limbs of DVT patients in observation group was (85.07±11.96) %, and the rate of venous patency was (89.00±25.33) %, and that of control group was (70.85±21.73) %, (75.00±35.36) %, and the differences were statistically significant (all P<0.05). The rate of bleeding events was lower in the observation group than in the control group, and the difference was statistically significant ( P<0.05). The difference in hospitalization satisfaction between the two groups was not statistically significant ( P>0.05) . Conclusions:The bleeding risk graded management program developed after comprehensive assessment can realize the balance between the therapeutic benefit and bleeding risk of CDT for DVT patients, and can improve the safety and effectiveness of CDT.
