Influence of imaging parameters on dosimetric parameters of lung in radiotherapy of thoracic esophageal cancer
10.13267/j.cnki.syzlzz.2025.052
- VernacularTitle:胸段食管癌放疗影像学特征参数对肺剂量学参数的影响研究
- Author:
Yanhong MOU
1
;
Peng LIANG
1
;
Qiang LIU
1
;
Zhiqian DU
1
Author Information
1. 重庆大学附属三峡医院肿瘤中心,重庆 404000
- Publication Type:Journal Article
- Keywords:
esophageal carcinoma;
intensity modulated radiotherapy;
imaging parameters;
dosimetric parameters
- From:
Practical Oncology Journal
2025;40(4):347-353
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influence of imaging parameters on the dosimetric parameters of the lung in intensity modulated radiotherapy(IMRT)for thoracic esophageal cancer,and provide a guideline for dose limitation in IMRT for thoracic esophageal cancer.Methods The imaging and pulmonary dosimetric parameters were collected from 142 patients with thoracic esophageal cancer receiving IMRT at Chongqing University Three Gorges Hospital from February 2017 to January 2019.The linear correlation analysis between the im-aging parameters and pulmonary dosimetric parameters was conducted using bivariate Pearson test.The regression model was established by multiple linear regression.Results The maximum transverse diameter of planning target volume(PTV)was moderately correlated with lung V30 and mean lung dose(MLD,both 0.40,all P<0.05).The volume of PTV intersecting with the lung was moderately positively correlated with lung V20,V30,and MLD(all 0.4