Latent profile analysis of financial toxicity among caregivers of cancer patients with chemotherapy and its relationship with post-traumatic stress disorder
10.3760/cma.j.cn115682-20240515-02743
- VernacularTitle:癌症化疗患者照顾者经济毒性的潜在剖面分析及与创伤后应激障碍的关系
- Author:
Haifeng WANG
1
;
Jihong FANG
;
Limin WANG
;
Xuejie YU
Author Information
1. 安徽医科大学护理学院，合肥 230001
- Publication Type:Journal Article
- Keywords:
Chemotherapy;
Chemotherapy;
Caregivers;
Financial toxicity;
Post-traumatic stress disorder;
Latent profile analysis
- From:
Chinese Journal of Modern Nursing
2025;31(6):771-778
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the latent categories of financial toxicity among caregivers of cancer patients with chemotherapy and to analyze the relationship between each category and post-traumatic stress disorder (PTSD) .Methods:Convenience sampling was used to select 256 cancer patients with chemotherapy in the Department of Oncology Chemotherapy and the Department of Daytime Chemotherapy in the South Zone, and the Department of Oncology Chemotherapy in the West Zone of the First Affiliated Hospital of University of Science and Technology of China from February to April 2024 for the study. General Information Questionnaire, Financial Toxicity Scale for Cancer Family Caregivers, and Impact of Event Scale-Revised were used to survey the study participants. Latent categories of financial toxicity were analyzed using Mplus 8.0. Ordered Logistic regression was used to analyze the influencing factors of latent categories of financial toxicity among caregivers of cancer patients with chemotherapy. Multiple linear regression was used to analyze the relationship between latent categories of financial toxicity and PTSD.Results:A total of 256 questionnaires were distributed and 242 valid questionnaires were recovered, with an effective recovery rate of 94.53% (242/256) . The financial toxicity of 242 caregivers of cancer patients undergoing chemotherapy were classified into three latent categories, including low financial toxicity-low behavior change group (9.92%) , moderate financial toxicity-moderate coping potential group (36.78%) , and high financial toxicity-high coping difficulty group (53.31%) . Ordered Logistic regression analysis showed that work status, occupation, and educational level were influencing factors of potential categories of financial toxicity for caregivers of cancer patients undergoing chemotherapy ( P<0.05) . Caregivers in moderate financial toxicity-moderate coping potential group and high financial toxicity-high coping difficulty group had more severe PTSD compared with caregivers in low financial toxicity-low behavior change group ( P<0.01) . Conclusions:Financial toxicity of caregivers of cancer patients undergoing chemotherapy can be categorized into three latent categories, with differences in levels of PTSD in caregivers across financial toxicity categories. It is recommended that healthcare professionals carry out targeted management based on a homogeneous group of financially toxic caregivers of cancer patients undergoing chemotherapy to alleviate their PTSD.
