An Analysis of Clinical Trial Registration Characteristics for Traditional Chinese Medicine in the Treatment of Overweight/Obesity
- VernacularTitle:中医药治疗超重/肥胖的临床试验注册特征分析
- Author:
Rumeng MEI
1
;
Ningzi ZANG
;
Chengjun GONG
;
Tianshu GAO
;
Xiao YANG
;
Libin ZHAN
;
Pin LI
Author Information
- Publication Type:Journal Article
- Keywords: Overweight; Obesity; Clinical trial registration; Traditional Chinese medicine; Evidence-based medicine; Characteristic analysis
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2025;27(10):2999-3009
- CountryChina
- Language:Chinese
- Abstract: Objective To systematically review and analyze the characteristics and current status of registered clinical trials on Traditional Chinese Medicine(TCM)for the prevention and treatment of overweight/obesity.Methods We conducted a comprehensive search of two primary clinical trial registration platforms,the Chinese Clinical Trial Registry and ClinicalTrials.gov,to extract registered information on TCM interventions for overweight/obesity.The search period spanned from the establishment of each registry to December 31,2024.Statistical analysis was performed on the extracted registration data.Results A total of 226 clinical studies were included,with a cumulative sample size of 25165 participants.The annual registration volume exhibited a significant upward trend.The majority of studies were interventional in design,with primary outcome measures focusing on anthropometric and metabolic indicators.Notably,only two trials fully met the international standards for clinical trial registration as outlined by the World Health Organization(WHO).Conclusion A quality assessment of the overall registration data revealed that the quality of trial registrations remains suboptimal.Issues such as inadequate standardization,transparency,and comprehensiveness were identified.Additionally,the geographical distribution of registered trials was uneven,and there is an urgent need to refine outcome measures related to TCM syndrome differentiation.
