Effects of risk management combined with exercise intervention on myocardial marker levels,cardiac function,quality of life and exercise endurance in elderly patients with acute myocardial infarction
10.3969/j.issn.1008-0074.2025.05.19
- VernacularTitle:风险管理联合运动干预对老年急性心肌梗死患者心肌标志物水平、心功能、生活质量与运动耐力的影响
- Author:
Chun-yu LIU
1
;
Lan QIN
;
Shuang LIU
;
Shuo LI
Author Information
1. 首都医科大学附属北京友谊医院急诊科,北京 100000
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Exercise therapy;
Quality of life
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2025;34(5):699-704
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of risk management combined with exercise intervention on myocardial mark-er levels,cardiac function,quality of life,exercise endurance and incidence of adverse events in elderly patients with acute myocardial infarction(AMI).Methods:This randomized controlled study enrolled 122 elderly AMI patients treated in Bei-jing Friendship Hospital,Capital Medical University between March 2021 and March 2023.Patients were randomly divided into control group(n=61)and intervention group(n=61).Patients in the control group were given conventional man-agement mode intervention,while those in the intervention group were given additional risk management combined exercise intervention.Both groups received intervention for 2 months,then followed up for 1 month.Myocardial markers,cardiac function,quality of life,exercise endurance and incidence of adverse events were compared between the two groups.Re-sults:Compared to those in the control group,patients in the intervention group had significantly lower levels of cardiac troponin I(cTnI)[(1.70±0.66)ng/mlvs.(2.32±0.90)ng/ml],brain natriuretic peptide(BNP)[(55.19±6.95)pg/ml vs.(85.25±8.12)pg/ml],left ventricular end-diastolic diameter(LVEDd)[(47.30±3.53)mm vs.(52.92±4.44)mm],left ventricular end-systolic diameter(LVESd)[(33.67±2.99)mm vs.(39.45±3.77)mm](P＜0.001 all),and significantly higher left ventricular ejection fraction(LVEF)[(69.97±5.21)％vs.(57.02±5.24)％],Seattle angina questionnaire(SAQ)score[(80.70±7.68)points vs.(75.57±7.77)points]and 6 min walking distance(6MWD)[(385.96±21.99)m vs.(339.51±24.49)m](P＜0.001 all).There was significant lower total incidence of adverse events(7.02％vs.21.67％)in intervention group after intervention(P=0.025).Conclusion:Risk management combined with exercise intervention may significantly reduce the levels of myocardial markers,improve cardiac function,quality of life,exercise endurance and reduce the occurrence of adverse events in elderly AMI patients.
