Research progress of adiponectin in the regulation of cardiovascular system
10.3969/j.issn.1008-0074.2025.05.27
- VernacularTitle:脂联素对心血管系统调控作用的研究进展
- Author:
Chao REN
1
;
Bo ZHANG
1
;
Shi-feng LIU
1
;
Yong ZHANG
1
;
Jia-li LIANG
1
;
Tong-jian WANG
1
Author Information
1. 中国人民解放军联勤保障部队第九六○医院心血管外科,山东济南 250031
- Publication Type:Journal Article
- Keywords:
Cardiovascular diseases;
Adiponectin;
Prognosis
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2025;34(5):744-748
- CountryChina
- Language:Chinese
-
Abstract:
As an important endocrine organ of human body,adipose tissue secrets a large amount of endocrine fac-tors that regulate a variety of physiological functions,and role of adiponectin in cardiovascular system is especially important.At the cellular and molecular level,adiponectin possesses profound anti-inflammatory,anti-oxidative and anti-apoptotic effects,which can reduce various pathogenic factors of cardiovascular diseases(CVD).In ad-vanced stage of CVD,the expression of adiponectin in adipose tissue as well as its circulating level compensatively increased.Therefore,adiponectin has a protective effect on the cardiovascular system,and increased adiponectin level may suggest severe CVD.In this review article,we systematically introduced the role of adiponectin in CVD and discussed its application prospects as a clinical biomarker.
