Clinic significance of allergen serum immunoglobulin E detection for the flying personnel with allergic rhinitis
10.3760/cma.j.issn.1007-6239.2017.04.006
- VernacularTitle:变应原血清免疫球蛋白E检测对飞行人员变应性鼻炎的临床意义
- Author:
Xuhui TAI
1
;
Kai LI
;
Yongxin LIAN
;
Xiaohui ZHANG
;
Xiuming WANG
;
Debao LIU
;
Xin YANG
;
Yanling CHU
;
Qiang XUE
Author Information
1. 解放军第四六三医院耳鼻喉科,沈阳,110042
- Publication Type:Journal Article
- Keywords:
Rinitis,allergic,perennial;
Allergens;
Immunoglobulin E;
Serum;
Flying personnel
- From:
Chinese Journal of Aerospace Medicine
2017;28(4):272-276
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinic significance of allergen serum immunoglobulin E (IgE) detection for the flying personnel with allergic rhinitis.Methods One hundred and twentyeight flying personnel with clinically suspected allergic rhinitis were drawn 2 ml venous blood.Serum tIgE (total IgE) and 14 allergen sIgE (specific IgE) including 7 aspiration allergens and 7 food allergens were detected with antibody kit.Strong positive reaction rates of the flying personnel with aspiration allergens and food allergens were compared as well as the correlation of serum tIgE and positive reaction rate of allergen sIgE was analyzed.Results Positive reaction rate of tIgE in 128 flying personnel with allergic rhinitis was 85.9 ％ (110/128) and positive reaction rate of sIgE was 91.4％ (117/128).The top 3 positive reaction rates of aspiration allergens were dust mite (66.4％),tree combination (32.8％) and house dust (23.4％).The top 3 positive reaction rates of food allergens were fruit combination (mango/pineapple/apple/peach/strawberry) (18.0％),seafood combination (shrimp/crab/scallop) (16.4％) and fish combination (ling/trout/weever) (13.3％).Positive response rate of the flying personnel with both aspiration and food allergens was 12.5 ％ (16/128).The aspiration allergens mainly reflected as strong positive reaction while the food allergens mainly expressed as weakly positive reaction.The strong positive reaction showed significance between aspiration and food allergens.(x2=16.881,P＜0.05).The strong positive reaction of allergen serum had the positive correlation to tIgE value (r=0.517,P＜0.01).Conclusions The allergen serum IgE detection have shown its objective,accurate and noninvasive advantages and are with less age,disease,medication,manipulation and other external limitations.The test results can be quantitatively or semi-quantitatively expressed and can determine tIgE level within the detection.So it has certain clinical significance on diagnosis,treatment,evaluation and prevention for the flying personnel with allergic rhinitis.
