Research advances in circadian clock genes in the development,progression,and treatment of liver cancer
- VernacularTitle:生物钟基因在肝癌发生发展与治疗中的研究进展
- Author:
Yanan KONG
1
;
Jiangkai LIU
Author Information
- Publication Type:Journal Article
- Keywords: Carcinoma,Hepatocellular; Biological Clocks; Circadian Rhythm; Genes,Tumor Suppressor
- From: Journal of Clinical Hepatology 2025;41(7):1431-1436
- CountryChina
- Language:Chinese
- Abstract: Primary liver cancer is one of the most common malignant tumors of the digestive system,and its morbidity and mortality rates are increasing year by year.Recent studies have shown that circadian clock gene disorders are closely associated with the development and progression of liver cancer,which provides a new perspective for the prevention,diagnosis,treatment,and prognosis of liver cancer.In addition,targeting circadian clock genes also shows a certain clinical application potential in the treatment of cancer.This article reviews the latest research advances in the role of circadian clock genes in the pathogenesis,prevention,treatment,and prognosis of liver cancer,in order to provide new ideas for the clinical diagnosis and treatment of liver cancer.
