Research progress on caffeine citrate for the prevention and treatment of bronchopulmonary dysplasia
10.3760/cma.j.cn101070-20241104-00715
- VernacularTitle:枸橼酸咖啡因防治支气管肺发育不良的研究进展
- Author:
Hui SHI
1
;
Yiwen WANG
1
Author Information
1. 上海交通大学医学院新华医院新生儿科,上海 200092
- Publication Type:Journal Article
- Keywords:
Caffeine citrate;
Bronchopulmonary dysplasia;
Lung injury;
Alveolar development
- From:
Chinese Journal of Applied Clinical Pediatrics
2025;40(11):865-868
- CountryChina
- Language:Chinese
-
Abstract:
As a classic medication in neonatal intensive care units, caffeine citrate has a significant clinical benefits, especially in preventing bronchopulmonary dysplasia (BPD), showing significant clinical potential.This article reviews the latest research progress of caffeine citrate in the prevention and treatment of BPD, with a focus on analyzing its cellular targets and potential mechanisms for lung protection.At the same time, this article also proposes issues worth exploring in future research on the mechanism of BPD, aiming to provide more effective intervention strategies for the treatment of premature infants with BPD.