Research progress on angiotensin-converting enzyme 2 in pediatric respiratory diseases
10.3760/cma.j.cn101070-20241006-00639
- VernacularTitle:血管紧张素转换酶2在儿童呼吸系统疾病中的研究进展
- Author:
Lannan YANG
1
;
Lili SHAO
;
Jiamin ZHAO
;
Xia DING
;
Qian NI
Author Information
1. 兰州大学第二临床医学院，甘肃 730030
- Publication Type:Journal Article
- Keywords:
Child;
Angiotensin-converting enzyme 2;
Corona virus disease 2019;
Acute respiratory distress syndrome;
Community-acquired pneumonia;
Asthma
- From:
Chinese Journal of Applied Clinical Pediatrics
2025;40(10):791-795
- CountryChina
- Language:Chinese
-
Abstract:
Angiotensin-converting enzyme 2 (ACE2) is known for its role in regulating blood pressure and electrolyte balance, but it has also been identified as the functional receptor for coronaviruses.With the global spread of corona virus disease 2019, the role of ACE2 across different age groups, particularly in children, has garnered increasing attention.Studies indicate that the distribution of ACE2 in the respiratory systems of children and adults differs significantly, which implies a distinct functional role in pediatric respiratory diseases.This paper reviews the latest research progress on ACE2 in children′s diseases such as corona virus disease 2019, acute respiratory distress syndrome, community-acquired pneumonia, and asthma.
