Roles of melanocyte stem cells in hair follicles in hair graying
- VernacularTitle:毛囊黑素干细胞在白发中的研究进展
- Author:
Feng WANG
1
;
Rushan XIA
1
Author Information
- Publication Type:Journal Article
- Keywords: Hair follicle; Stem cells; Melanocytes; Hair graying; Signal transducing pathway; Hair repigmentation
- From: Chinese Journal of Dermatology 2025;58(2):182-185
- CountryChina
- Language:Chinese
- Abstract: Hair graying is a common phenomenon associated with aging, and the excessive differentiation of melanocyte stem cells in hair follicles has gradually gained attention for its role in the occurrence and development of hair graying. The cyclical nature of hair follicles provides an excellent model for studying stem cells. With the continuous development of mouse models and cell transplantation technologies, the understanding of hair graying and aging has been steadily deepening, though many questions remain unanswered. This review focuses on the origins and biological characteristics of melanocyte stem cells and their related signaling pathways. It further explains the relationship between melanocyte stem cells and hair graying, as well as the role of some drugs in hair repigmentation.
