Advances in genetic research on pleuropulmonary blastoma in children
10.3760/cma.j.cn101070-20240616-00373
- VernacularTitle:儿童胸膜肺母细胞瘤遗传学研究进展
- Author:
Mingzhu SU
1
;
Yan SU
1
Author Information
1. 国家儿童医学中心，首都医科大学附属北京儿童医院肿瘤内科，首都医科大学基础－临床联合实验室（儿童肿瘤发病机制与创新药物研究实验室），儿童肿瘤国家临床重点专科，儿科重大疾病研究教育部重点实验室，北京 100045
- Publication Type:Journal Article
- Keywords:
Pleuropulmonary blastoma;
Genetics;
Research progress
- From:
Chinese Journal of Applied Clinical Pediatrics
2025;40(5):386-388
- CountryChina
- Language:Chinese
-
Abstract:
Pleuropulmonary blastoma (PPB) is the most common primary malignancy of the lungs in children.It is now widely believed that the disease is closely related to genetic variation in patients, especially DICER1 gene mutations.Having the knowledge of genetic variations in children is of great significance for the identification of high-risk groups, disease diagnosis and identification, and the formulation of disease surveillance strategies.Therefore, the genetic progress of pediatric PPB was reviewed in this article.
