Analysis of the cause of hematochezia in children hospitalized in department of digestive infection: a single center retrospective study over 10 years
10.3760/cma.j.cn101070-20240919-00603
- VernacularTitle:消化感染科住院患儿便血的病因分析：单中心10年回顾性研究
- Author:
Huajie LIU
1
;
Feifei SONG
1
Author Information
1. 上海交通大学医学院附属儿童医院消化感染科，上海 200062
- Publication Type:Journal Article
- Keywords:
Child;
Hematochezia;
Gastrointestinal hemorrhage;
Pathogeny
- From:
Chinese Journal of Applied Clinical Pediatrics
2025;40(5):368-371
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the etiology, improve clinical diagnosis, treatment and prognosis of children with hematochezia.Methods:Retrospective cohort study.The clinical data of 639 children with hematochezia admitted to the Department of Digestive Infection, Shanghai Children′s Hospital, School of Medicine, Shanghai Jiao Tong University, during January 2014 to January 2024 were analyzed.639 children were divided into five groups according to their ages.There were 55 cases as infant group (>28 days to 1 year old), 165 cases as toddler group (>1 to 3 years old), 195 cases as preschool age group (>3 to 6 years old), 159 cases as school age group (>6 to 12 years old), and 65 cases as adolescent group (>12 to 18 years old).Statistical analysis was conducted for the hemorrhage site and etiology of hematochezia.Count data was described using examples and percentages. Inter group comparison was assessed with Chi-square test.Results:(1) Among 639 children with hematochezia, lower gastrointestinal bleeding (LGIB) was the main site(75.0%, 479/639).The top 6 etiologies of hematochezia were intestinal polyps(28.6%, 183/639), infective enteritis(17.4%, 111/639), allergic enteritis(7.4%, 47/639), duodenal ulcers(6.9%, 44/639), colitis (6.1%, 39/639) and inflammatory bowel diseases(5.6%, 36/639).(2) The average age of the 639 cases was 4.96 years, and the male to female ratio was 1.61∶1.00.There was no statistically significant difference in age, hemorrhage site and etiology between girls and boys ( χ2=6.146, 2.647, 4.282, all P>0.05).(3) The top two causes in each age group are infectious enteritis and allergic enteritis in the infant group and toddler group, intestinal polyps and infectious enteritis in preschool group, intestinal polyps and duodenal ulcers in school age group, inflammatory bowel disease and colitis in adolescent group.There were statistically significant differences in hemorrhage site and etiology among different age groups( χ2=55.890, 284.378, all P<0.001).(4) The median age of 183 cases of hematochezia caused by intestinal polyps was 4.00 years.Intestinal polyps were common in the preschool group. Conclusions:LGIB is the main hemorrhage site in children with hematochezia.The etiologies of hematochezia in different age groups are different.The most common etiologies are infective enteritis and allergic enteritis in infants, and intestinal polyps, intestinal bowel disease in children.
