Research progress on the role of platelets in the development of Kawasaki disease and coronary artery lesions
10.3760/cma.j.cn101070-20240220-00099
- VernacularTitle:血小板在川崎病及冠状动脉病变中的作用研究进展
- Author:
Jiahui MENG
1
;
Fang LIU
1
Author Information
1. 复旦大学附属儿科医院心血管中心,上海 201102
- Publication Type:Journal Article
- Keywords:
Platelet;
Kawasaki disease;
Coronary artery lesion;
Coronary artery aneurysm
- From:
Chinese Journal of Applied Clinical Pediatrics
2025;40(1):68-70
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease (KD) is an acute systemic vasculitis that can lead to coronary artery lesions (CAL), and become the leading cause of acquired heart disease in children.In recent years, increasing attention has been paid to the role of platelets in the development of KD and its cardiovascular complications.Platelet activation is closely associated with thrombus formation and immune-inflammatory responses.In this review, the latest literature is examined to investigate the role of platelets in the occurrence of KD and CAL.