Multidimensional analysis of cranio-maxillofacial joint-neural interactions and their clinical significance
10.3760/cma.j.cn112144-20250319-00092
- VernacularTitle:颅颌面骨关节的神经调控机制及其临床意义
- Author:
Kai JIAO
1
Author Information
1. 空军军医大学唐都医院口腔科，西安710038
- Publication Type:Journal Article
- Keywords:
Bone remodeling;
Neural crest;
Nervous system;
Skeleton;
Temporomandibular joint
- From:
Chinese Journal of Stomatology
2025;60(7):697-703
- CountryChina
- Language:Chinese
-
Abstract:
The interplay between the skeletal and nervous systems has emerged as a pivotal area in modern medical research. Unlike mesodermal-origin trunk skeletons, craniofacial bones demonstrate distinctive neurobiological properties due to their unique embryonic origin from ectodermal neural crest cells. This article systematically investigates the interaction mechanisms between craniofacial bones and the nervous system across developmental, anatomical, and functional dimensions. It comprehensively elaborates the translational value of this neuro-skeletal association in advancing precision diagnosis and treatment for various pathologies, including temporomandibular joint osteoarthritis, craniofacial bone trauma, and dentition defect restoration. The findings propose novel strategies spanning molecular regulation to clinical translation, offering innovative perspectives for managing craniofacial disorders.
