Transformation and evidence-based progress of chronic constipation treatment mode
10.3760/cma.j.cn441530-20251013-00379
- VernacularTitle:慢性便秘治疗模式的转变与循证进展
- Author:
Yansen HUANG
1
;
Weidong TONG
1
;
Guodong XIAO
1
;
Qing LI
1
;
Man GUO
1
Author Information
1. 陆军军医大学大坪医院（陆军特色医学中心）普通外科，重庆 400042
- Publication Type:Journal Article
- Keywords:
Constipation;
Treatment;
Surgery;
Fecal microbiota transplantation;
Sacral neuromodulation
- From:
Chinese Journal of Gastrointestinal Surgery
2025;28(12):1411-1416
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, significant progress has been made in the treatment of chronic constipation, with high-quality studies emerging in areas such as fecal microbiota transplantation (FMT), sacral neuromodulation (SNM), acupuncture, and surgical techniques. The therapeutic approach is shifting from a traditional "medication and surgery" model toward an integrated strategy that includes dietary and defecation habit adjustment, FMT, SNM, acupuncture, pharmacotherapy, and surgery. Although FMT can partially improve stool frequency and consistency, its standardization and long-term efficacy require further validation. SNM demonstrates limited effectiveness in treating chronic constipation and is relatively cost-inefficient. Electroacupuncture remains controversial, though some studies support its value. Biofeedback therapy is recommended by multiple guidelines as the first-line treatment for dyssynergic defecation (DD), with portable home-based biofeedback systems showing considerable potential. For internal rectal prolapse (IRP) and rectocele (RC), various surgical options exist without a clear superiority, though laparoscopic ventral rectopexy (VMR) is increasingly favored due to its low recurrence rate and high patient satisfaction. In the surgical management of slow transit constipation (STC), total colectomy with ileorectal anastomosis remains the mainstream approach, while subtotal colectomy is gaining attention as an alternative.
