Effect of Nuan'gong Decoction on the Menstrual Status and Uterine Artery Blood Flow in Patients with Cold Coagulation and Blood Stasis Type Oligomenorrhea
10.11969/j.issn.1673-548X.2025.03.016
- VernacularTitle:暖宫汤对寒凝血淤型月经量少患者月经状况及子宫动脉血流的影响
- Author:
Hongyu MA
1
;
Wenqing PIAO
;
Hua YANG
Author Information
1. 161000 齐齐哈尔市中医医院妇科
- Publication Type:Journal Article
- Keywords:
Oligomenorrhea;
Cold coagulation and blood stasis type;
Nuan'gong decoction;
Menstrual condition;
Uterine arterial blood flow
- From:
Journal of Medical Research
2025;54(3):85-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of Nuan'gong decoction in the treatment of cold coagulation and blood stasis type menorrhagia.Methods A total of 120 patients with oligomenorrhea were selected and divided into two groups according to random number table method:estrogen and progesterone group and Nuan'gong decoction.The estrogen and progesterone group was treated with se-quential estrogen and progesterone therapy,while the Nuan'gong decoction group was treated with Nuan'gong decoction on the top of the estrogen and progesterone group.The therapeutic effects,menstrual status,and changes in uterine artery blood flow were compared be-tween the two groups.Results The total effective rate of the Nuan'gong decoction group was 91.67％,which was greatly higher than the 76.67％of the estrogen and progesterone group(P＜0.05).After treatment,the traditional Chinese medicine syndrome score and men-strual distress questionnaire(MDQ)Chinese version score of the Nuan'gong decoction group were lower than those of the estrogen and progesterone group(P＜0.05).After treatment,the duration of menstruation in the Nuan'gong decoction group was longer than that in the estrogen and progesterone group(P＜0.05),and the pictorial blood loss assessment chart(PBAC)score was higher than that in the estrogen and progesterone group(P＜0.05).After treatment,the levels of progesterone(P),estradiol(E2),luteinizing hormone(LH),and follicle stimulating hormone(FSH)in the Nuan'gong decoction group were higher than those in the estrogen and progesterone group(P＜0.05).After treatment,the uterine artery pulsatility index(PI),resistance index(BI)and systolic/diastolic peak flow ve-locity(S/D)in the Nuan'gong decoction group were lower than those in the estrogen and progesterone group.Conclusion For patients with cold coagulation and blood stasis type oligomenorrhea,Nuan'gong decoction for traditional Chinese medicine syndrome differentiation treatment can achieve great therapeutic effects,effectively prolong the duration of menstruation,restore menstrual flow and sex hormone levels,and improve the blood flow parameters of uterine artery.
