Current status of diagnosis and treatment of gastroesophageal reflux disease and reflection on surgical anti-reflux mechanisms
10.3760/cma.j.cn441530-20250616-00222
- VernacularTitle:胃食管反流病诊疗现状及外科手术抗反流机制的思考
- Author:
Zheqi ZHOU
1
;
Aili AIKEBAIER
;
Abudureyimu KELIMU
Author Information
1. 新疆维吾尔自治区人民医院微创、疝和腹壁外科，普外微创研究所，乌鲁木齐 830001
- Publication Type:Journal Article
- Keywords:
Gastroesophageal reflux disease;
Fundoplication;
Esophageal hiatal hernia;
Phrenoesophageal ligament
- From:
Chinese Journal of Gastrointestinal Surgery
2025;28(10):1105-1111
- CountryChina
- Language:Chinese
-
Abstract:
Gastroesophageal reflux disease (GERD) is a chronic digestive system disorder triggered by multiple factors, which is clinically prevalent and affects patients' quality of life. Laparoscopic fundoplication serves as the mainstay of surgical treatment for GERD, requiring standardized preoperative examinations to assess patients' reflux status and esophageal motility for individualized selection of fundoplication techniques. Intraoperative regulation of the fundoplication tension with a bougie aims to balance the anti-reflux efficacy and the risk of postoperative dysphagia. Additionally, membranous anatomy research guided by embryonic development facilitates optimization of surgical approaches and provides a theoretical basis for surgical innovation. This article deeply discusses the status of GERD diagnosis and treatment, as well as the surgical anti-reflux mechanisms, from multiple aspects including pathogenesis, diagnosis, and surgical management. We also contemplate the existing challenges in the embryonic development and anatomy of the anti-reflux barrier.
