Hotspot issues and future directions in the research of anti-bacterial agent-associated acute kidney injury in children
10.3760/cma.j.cn114015-20250424-00225
- VernacularTitle:儿童抗菌药物相关急性肾损伤研究热点与未来方向
- Author:
Jianjiang ZHANG
1
;
Wenjie DOU
1
Author Information
1. 郑州大学第一附属医院儿科，河南省儿童肾脏病临床诊疗中心，郑州 450052
- Publication Type:Journal Article
- Keywords:
Anti-bacterial agents;
Acute kidney injury;
Child
- From:
Adverse Drug Reactions Journal
2025;27(6):321-324
- CountryChina
- Language:Chinese
-
Abstract:
Due to physiological and metabolic characteristics and disease characteristics being different from adults, such as the high incidence of infectious diseases, children are at a high-risk of acute kidney injury (AKI) related to anti-bacterial agents, and there were many challenges in prevention and treatment. The hot issues in the research of anti-bacterial agent-related AKI in children, including the study of nephrotoxicity mechanism of anti-bacterial agents, the exploration of early biomarkers, and the optimization of treatment strategies, are expounded in this article. In the future, it is recommended to strengthen researches on child specificity, deepen basic researches, optimize monitoring plans for pediatric treatment drugs, and establish a pediatric drug monitoring system, so as to provide references for rational clinical drug use of the anti-bacterial agents and further researches on AKI.
