Mediating effect of facial emotion recognition ability in patients with schizophrenia between neurocognition and social functioning
10.3969/j.issn.1000-6729.2025.02.01
- VernacularTitle:精神分裂症患者的面孔情绪识别能力在神经认知与社会功能间的中介作用
- Author:
Haitao CHEN
1
;
Wei QU
1
;
Jiaqi SONG
1
;
Meng ZHANG
1
;
Hongzhen FAN
1
;
Shuping TAN
1
Author Information
1. 北京回龙观医院,北京大学回龙观临床医学院,北京 100096
- Publication Type:Journal Article
- Keywords:
schizophrenia;
social functioning;
neurocognition;
facial emotion recognition;
causal mediation analysis
- From:
Chinese Mental Health Journal
2025;39(2):101-106
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the mechanism of how neurocognition affects social functioning through fa-cial emotion recognition in individuals with schizophrenia.Methods:Totally 203 patients with schizophrenia meet-ing the Diagnostic and Statistical Manual of Mental Disorders,Fourth Edition(DSM-IV)diagnostic criteria were re-cruited,with an age of(40±12)years,an initial onset age of(24±8)years,scored(60.4±16.1)points on the Positive and Negative Syndrome Scale.Using the Personal and Social Performance Scale(PSP),the MATRICS Consensus Cognitive Battery(MCCB),and the Facial Emotion Recognition Test(FERT)to assess patients'social functioning,neurocognition,and facial emotion recognition abilities.Results:In the relationship between MCCB fac-tor scores and PSP dimensions scores,happy face recognition showed a mediating effect in socially useful activities dimension(ACME=0.021,P＜0.01),sad(ACME=-0.026,P＜0.05)and surprised face recognition(ACME=-0.017,P＜0.05)showed mediating effects in self-care dimension.Additionally,sad(ACME=-0.025,P＜0.05)and fearful face recognition(ACME=-0.025,P＜0.001)played a mediating role in disruptive and aggres-sive behavior dimensions.Conclusion:Facial emotion recognition in patients with schizophrenia may play a media-ting role in the neurocognitive mechanisms of social dysfunction,with different dimensions of social dysfunction be-ing associated with specific categories of emotions.
