Evidence map on the treatment of heart failure with Yiqifumai injec-tion
10.12092/j.issn.1009-2501.2025.02.009
- VernacularTitle:注射用益气复脉治疗心力衰竭的证据图谱研究
- Author:
Shichao LYU
1
;
Yunjiao WANG
;
Yiming ZUO
;
Hongcai SHANG
Author Information
1. 天津中医药大学第一附属医院(国家中医针灸临床医学研究中心),天津 300381;北京中医药大学东直门医院,中医内科学教育部和北京市重点实验室,北京 100700
- Publication Type:Journal Article
- Keywords:
Yiqifumai injection;
heart failure;
evi-dence map;
clinical research
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(2):222-231
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To display the distribution of evi-dence in the field of Yiqifumai injection treatment for heart failure.METHODS:To retrieve relevant da-tabases such as CBM,CNKI,Wanfang,VIP,Co-chrane Library,PubMed,Embase,and Web of Sci-ence,and search for the China Clinical Trial Regis-try,ClinicalTrials.gov and collect clinical studies,sys-tematic evaluations,and guideline studies on the treatment of heart failure with Yiqifumai injection.The evidence map research method use a table to display the proportion of literature,sample size,co-morbidities,and quality evaluations of systematic evaluations.Use a pie chart to display the propor-tion distribution of research types,a line chart to describe publication trends,and a bubble chart to display the distribution of evidence.RESULTS:The overall number of articles on the treatment of heart failure with Yiqifumai injection is in a steady development stage.Clinical studies are mainly small sample,single center,short-term randomized controlled trials,with a sample size of 60-100 cases and an intervention duration of mostly 14 days.The underlying disease is mainly coronary heart dis-ease.Clinical research evidence tends to support the therapeutic effect of Yiqifumai injection com-bined with conventional Western medicine in im-proving heart failure patients'heart function and quality of life.However,there are also issues such as low overall quality of research,unreasonable clinical trial design,small sample size,incomplete selection of outcome indicators,low international recognition of certain outcome indicators,and lack of reporting on long-term outcomes The overall quality of randomized controlled trials andsystem-atic evaluation methodology is low.CONCLUSION:In the future,more large sample,multicenter clini-cal randomized controlled trials should be conduct-ed to obtain higher-level evidence-based medicine evidence to fully demonstrate the advantages of traditional Chinese medicine treatment,and pro-mote the common development of traditional Chi-nese medicine cardiology and evidence-based med-icine.
