A case of multiple organ dysfunction caused by acute glyphosate combined with alcohol poisoning

VernacularTitle:急性草甘膦合并乙醇中毒致多器官功能障碍1例
Author: Yuyang QIU ¹ ; Yimin MA ¹ ; Wei XIE ¹ ; Guiyun LI ¹
Author Information

1. 贵阳市第二人民医院急诊科，贵阳　550081
Publication Type:Journal Article
Keywords: Poisoning; Glyphosate poisoning; Alcohol poisoning; Multiple organ dysfunction syndrome; Continuous renal replacement therapy; Hemoperfusion
From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2025;43(8):625-628
CountryChina
Language:Chinese
Abstract: This study analyzes the clinical data of a patient presenting with acute poisoning following the co-ingestion of a pesticide (approximately 100-120 ml of 41% glyphosate-isopropylammonium) and alcohol (approximately 100 g of ethanol). The patient developed multiple organ dysfunction syndrome (MODS), manifesting as acute kidney injury (AKI), metabolic acidosis, hyperkalemia, acute lung injury (ALI), acute liver injury, acute intestinal injury, and systemic inflammatory response syndrome (SIRS). Following administration of general supportive care combined with continuous renal replacement therapy (CRRT) and hemoperfusion (HP), the patient recovered fully and was discharged. Acute combined glyphosate and ethanol poisoning can induce MODS. Analysis of this patient's diagnosis and treatment process enhances clinicians' understanding of this toxicological presentation and offers valuable clinical insights to improve survival rates in similar cases.