Summary of the best evidence for prevention of contrast-associated acute kidney injury after enhanced CT examination in patients with nephropathy
10.3760/cma.j.cn114015-20240403-00227
- VernacularTitle:肾病患者增强CT检查对比剂相关急性肾损伤预防的最佳证据总结
- Author:
Xinyu HAO
1
;
Lin ZHANG
;
Jiani ZHAO
;
Jing LYU
;
Lei ZHAO
;
Yiru ZHAO
;
Caihui ZHANG
;
Yueying ZHANG
Author Information
1. 山西医科大学护理学院，太原 030001
- Publication Type:Journal Article
- Keywords:
Contrast media;
Tomography scanners, X-ray computed;
Kidney diseases;
Acute kidney injury;
Prevention;
Evidence-based medicine;
Evidence summaries
- From:
Adverse Drug Reactions Journal
2024;26(10):594-600
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the relevant evidence for the prevention of contrast-associated acute kidney injury (CA-AKI) after enhanced CT examination in patients with nephropathy.Methods:The literature on prevention of CA-AKI in patients with nephropathy who underwent enhanced CT examination in relevant websites and medical literature databases at home and abroad were systematically searched, the quality of the literature was evaluated, and the relevant evidence was extracted and summarized. The retrieval period was from January 1, 2013 to December 1, 2023.Results:A total of 17 literature was included, including 6 guidelines, 5 expert consensuses, 2 clinical decisions, 2 cohort studies, 1 evidence summary and 1 systematic review. Evidence was extracted from these literature. After summary and analysis of these evidence, 10 evidence topics were sorted out, including threshold of estimated glomerular filtration rate and high-risk population, screening, hydration prevention, drug prevention, use of nephrotoxic drugs, use of metformin, precautions for dialysis patients, alternative imaging strategies, choice of iodine contrast agents, and points for attention after enhanced CT examination, forming 47 pieces of evidence.Conclusion:The relevant evidence for the prevention of CA-AKI can provide a more systematic evidence-based basis for medical staffs in screening high-risk population and preventing and managing CA-AKI in patients with chronic kidney disease before enhanced CT examination.
