Cranial MRI-based correlational study of enlarged perivascular spaces score and deep medullary vein score
10.19745/j.1003-8868.2025067
- VernacularTitle:基于颅脑MRI的脑血管周围间隙扩大评分与深髓静脉评分的相关性研究
- Author:
Wen SU
1
;
Hai-long JIANG
1
;
Xiao-yan LU
1
Author Information
1. 南京医科大学附属南京医院(南京市第一医院)医学影像科,南京 210006
- Publication Type:Journal Article
- Keywords:
enlarged perivascular space score;
deep medullary vein score;
susceptibility weighted imaging;
T2WI;
basal ganglia;
MRI
- From:
Chinese Medical Equipment Journal
2025;46(4):52-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between deep medullary vein(DMV)score and enlarged perivascular space(EPVS)score with cranial MRI to explore the mechanisms of EPVS occurrence and development.Methods Totally 118 patients with cerebral small vessel disease in some hospital had their clinical and imaging data analyzed retrospectively.On T2-weighted images,EPVS scores ranging from 0 to 4 were assigned to the basal ganglia and centrum semiovale regions based on the number of EPVS.For DMV scoring on magnetic susceptibility weighted images,the brain lobes were divided into six regions,including bilateral frontal,parietal and occipital lobes,and scored according to the significance and continuity of the DMV signals(0 to 3 points),and the scores of the regions were summed up as the total DMV score(0 to 18 points).Spearman correlation analysis was employed to investigate the correlation between DMV and EPVS scores.Kruskal-Wallis test was used to analyze the differences among groups with different EPVS scores.Additionally,multinomial ordinal regression analysis was conducted to explore the factors influencing EPVS.Results No significant correlation was found between EPVS scores in centrum semiovale and DMV scores(r2=0.015,P=0.191),while DMV scores and EPVS scores in basal ganglia showed a significant positive correlation(r2=0.558,P<0.000 1).Univariate analysis revealed statisti-cally significant differences in age,hypertension and DMV scores when different scoring groups of EPVS in the basal ganglia region were compared(P<0.05);multinomial ordinal regression analysis showed that age,hypertension and DMV scores were independently correlated with EPVS scores in the basal ganglia region.Conclusion There is a positive correlation between DMV scores and EPVS scores in the basal ganglia.Age,hypertension,and DMV score are independent influe-ncing factors for EPVS in the basal ganglia region.[Chinese Medical Equipment Journal,2025,46(4):52-56]
