The Predictive Value of Epicardial Adipose Thickness for Pre-eclampsia Evalu-ated by Echocardiography
- VernacularTitle:超声心动图评估心外膜脂肪层厚度对子痫前期的预测价值
- Author:
Qingqing ZHANG
1
;
Ming WEN
1
;
Qi CHEN
1
Author Information
1. 芜湖市第一人民医院产科,安徽 芜湖 241060
- Publication Type:Journal Article
- Keywords:
Preeclampsia;
Epicardial adipose thickness;
Echocardiography
- From:
Journal of Practical Obstetrics and Gynecology
2025;41(3):242-245
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the predictive value of epicardial adipose thickness(EAT)for pre-eclampsia(PE)evaluated by echocardiography.Methods:The clinical data of 242 early pregnant women admitted to Wuhu First People's Hospital from September 2020 to November 2023 were retrospectively analyzed.According to whether PE occurred,they were divided into PE group(n=31)and non-PE group(n=211).The echocardio-graphic data of pregnant women at 11+0-13+6 weeks of gestation were collected,and the influencing factors of PE in pregnant women were analyzed by multivariate logistic regression.Receiver operating characteristic(ROC)curve was drawn to evaluate the predictive value of EAT for PE in pregnant women.Results:There were statisti-cally significant differences in age,pregnancy mode,body mass index(BMI),history of hypertension,systolic and diastolic blood pressure,serum soluble vascular endothelial growth factor receptor-1(sFlt-1)/placental growth fac-tor(PLGF)ratio and EAT between PE group and non-PE group(P<0.05).Multivariate Logistic regression analy-sis showed that increased BMI(OR 1.492,95%CI 1.161-2.724),history of hypertension(OR 3.684,95%CI 2.074-6.542),increased serum sFlt-1/PLGF value(OR 1.982,95%CI 1.268-3.099),and increased EAT(OR 2.246,95%CI 1.292-3.903)were independent risk factors for PE in pregnant women(P<0.05).The results of ROC curve analysis showed that the area under the curve(AUC)of ultrasound evaluation of EAT in predicting PE in pregnant women was0.848(95%CI0.785-0.910,P<0.001).When the optimal cutoff value was5.63 mm,the sensitivity was 85.71%and the specificity was 67.14%.Conclusions:Ultrasound evaluation of EAT for PE pre-diction has good application value.
