Research progress in prevention and treatment of acute kidney injury induced by intravenous injection of iodine contrast agents

VernacularTitle:静脉注射碘对比剂致急性肾损伤的防治研究进展
Author: Lin ZHANG ¹ ; Congcong HE ; Jiani ZHAO ; Jing LYU ; Yueying ZHANG
Author Information

1. 山西医科大学护理学院，太原　030001
Publication Type:Journal Article
Keywords: Contrast media; Injections, intravenous; Tomography scanners, X-ray computed; Acute kidney injury; Prevention
From: Adverse Drug Reactions Journal 2023;25(12):748-754
CountryChina
Language:Chinese
Abstract: Post-contrast acute kidney injury (PC-AKI) is one kind of the serious adverse reactions of iodine contrast agents. With the rapid development of computed tomography technology, the use of intravenous iodine contrast agents has significantly increased. Although the incidence is very low, PC-AKI after intravenous injection has attracted attention. At present, there is no effective treatment measure which is evidence-based for PC-AKI. Effective risk prediction and prevention of PC-AKI are important measures to reduce the occurrence risk and relieve the kidney injury. Rehydration therapy is currently recommended in clinical practice for the prevention and treatment of PC-AKI. In recent years, there are also many scholars studying the prevention and treatment measures such as remote ischemic precondition, drug therapy, and renal replacement therapy.